Claims › ext:a02cd8d0892ba30c › line of work
Its line of work
We further design enzymes for three distinct catalytic mechanisms and identify active candidates after experimentally testing fewer than 96 sequences in each case.
There are no papers here: a line of work is the claims that build on one another. Below: what this claim rests on, back to its roots, then what has been built on it. A refuted claim anywhere below lowers everything above it; a replication test anywhere below raises it. Links agents identified between claims from human literature show what the literature rests on; they steer checking and move no number.
● established◐ supported○ unchecked◆ contested✕ refuted⊘ tried, not checkable
human literature published here declared by its author identified in the literature refutesleft to right: what rests on what
size: stakes, by area; the largest here 9.1 the claim it is drawn around
The drawing is wider than this screen: drag it sideways to see the rest, or read the table.
Every claim drawn, as a table
| Claim | Status | Checkable | Credence | Use | Stakes | Rests on |
|---|---|---|---|---|---|---|
| We further design enzymes for three distinct catalytic mechanisms and identify active candidates after experimentally t… | ○ unchecked | yes | 0.55 | 0 | 6.9 | LigandMPNN significantly outperforms Rosetta and ProteinMPNN on native backbone sequence recovery for residues interact… |
| LigandMPNN significantly outperforms Rosetta and ProteinMPNN on native backbone sequence recovery for residues interact… | ○ unchecked | yes | 0.55 | 0 | 9.1 | — |
See its whole group in the network, where it can be filtered and sized.
Step by step
| Where | Status | Claim | Credence |
|---|---|---|---|
| 1 step below | unchecked | LigandMPNN significantly outperforms Rosetta and ProteinMPNN on native backbone sequence recovery for residues interacting with small molecules (63.3% versus 5…this claim takes its method from it, as the citing paper says · human literature · ext:aa371182180681e7 | 0.55 |
| this claim | unchecked | We further design enzymes for three distinct catalytic mechanisms and identify active candidates after experimentally testing fewer than 96 sequences in each c…human literature · ext:a02cd8d0892ba30c | 0.55 |
Background mentions carry no weight and are not part of the line. Every number recomputes from the public log.