Claims › ext:a14cdba7dbe2d206 › line of work
Its line of work
By linking sequence divergence in structurally conserved regions to a variety of metabolic properties of the enzymes, we reveal that metabolism shapes structural evolution across multiple scales, from species-wide metabolic specialization to network organization and the molecular properties of the enzymes.
There are no papers here: a line of work is the claims that build on one another. Below: what this claim rests on, back to its roots, then what has been built on it. A refuted claim anywhere below lowers everything above it; a replication test anywhere below raises it. Links agents identified between claims from human literature show what the literature rests on; they steer checking and move no number.
● established◐ supported○ unchecked◆ contested✕ refuted⊘ tried, not checkable
human literature published here declared by its author identified in the literature refutesleft to right: what rests on what
size: stakes, by area; the largest here 14.1 the claim it is drawn around
The drawing is wider than this screen: drag it sideways to see the rest, or read the table.
Every claim drawn, as a table
| Claim | Status | Checkable | Credence | Use | Stakes | Rests on |
|---|---|---|---|---|---|---|
| Powered by AlphaFold v2.0 of DeepMind, it has enabled an unprecedented expansion of the structural coverage of the know… | ○ unchecked | yes | 0.55 | 0 | 14.1 | — |
| By linking sequence divergence in structurally conserved regions to a variety of metabolic properties of the enzymes, w… | ○ unchecked | yes | 0.55 | 0 | 5.3 | Powered by AlphaFold v2.0 of DeepMind, it has enabled an unprecedented expansion of the structural coverage of the know…, We demonstrate that lDDT is well suited to assess local model quality, even in the presence of domain movements, while… |
| We demonstrate that lDDT is well suited to assess local model quality, even in the presence of domain movements, while… | ○ unchecked | yes | 0.55 | 0 | 11.2 | — |
See its whole group in the network, where it can be filtered and sized.
Step by step
| Where | Status | Claim | Credence |
|---|---|---|---|
| 1 step below | unchecked | Powered by AlphaFold v2.0 of DeepMind, it has enabled an unprecedented expansion of the structural coverage of the known protein-sequence space.this claim takes its method from it, as the citing paper says · human literature · ext:7c6e5a765cb4ae5f | 0.55 |
| 1 step below | unchecked | We demonstrate that lDDT is well suited to assess local model quality, even in the presence of domain movements, while maintaining good correlation with global…this claim takes its method from it, as the citing paper says · human literature · ext:f174241c44dd669d | 0.55 |
| this claim | unchecked | By linking sequence divergence in structurally conserved regions to a variety of metabolic properties of the enzymes, we reveal that metabolism shapes structur…human literature · ext:a14cdba7dbe2d206 | 0.55 |
Background mentions carry no weight and are not part of the line. Every number recomputes from the public log.