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Keyword: ASD severity Clear all
3 claims from 1 paper
Neuroscience › Functional Brain Connectivity Studies
Dynamic Functional Connectivity Reveals Abnormal Variability and Hyper‐connected Pattern in Autism Spectrum Disorder
Li, Zhu, Nguchu et al. · Autism Research · 2019
Using dynamic functional connectivity on public brain imaging data from 62 autistic and 63 typically developing children, the study found greater connectivity variability and a more hyper-connected state in ASD.
Unchecked3 claimsShow 3 claims
- Unchecked“Our findings revealed higher DFC variability between the posterior cingulate gyrus (PCC) and middle temporal pole (TPOmid) in subjects with ASD.”
- Unchecked“The connection between the PCC and pars opercularis of inferior frontal gyrus (IFGoper) also presented greater variability in ASD, with the increase depending on ASD symptom severity.”
- UncheckedIn this study, autistic children spent longer in, and moved more often into, a globally hyper-connected brain state, possibly linked to variable PCC–IFGoper connection.“Furthermore, clustering analysis showed higher averaged dwell time and probability of transition for globally hyper‐connected state in the ASD group, which could be related to connection variability between the PCC and IFGoper.”
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