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Keyword: adolescent brain development ×Clear all

2 claims from 1 paper

1. Neuroscience › Functional Brain Connectivity Studies

   Adolescent development of multiscale structural wiring and functional interactions in the human connectome

   Park, Paquola, Bethlehem et al. · Proceedings of the National Academy of Sciences · 2022

   In 199 people aged 14 to 25 followed over time, the authors modelled cortical wiring with MRI and related its development to changes in resting-state functional connectivity.

   Unchecked2 claims
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   1. UncheckedAt the first scan, brain regions with more similar structural wiring tended to show more closely coupled functional activity.“At baseline, regions with more similar structural wiring were more likely to be functionally coupled.”
   2. UncheckedIn this adolescent cohort, structural networks growing more distinct, especially sensory/unimodal versus default mode, went with weaker functional interactions.“Moreover, correlating longitudinal structural wiring changes with longitudinal functional connectivity reconfigurations, we found that increased structural differentiation, particularly between sensory/unimodal and default mode networks, was reflected by reduced functional interactions.”