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Status: Unchecked ×Keyword: brain functional connectivity ×Clear all

2 claims from 1 paper

1. Neuroscience › Functional Brain Connectivity Studies

   General anaesthesia decreases the uniqueness of brain functional connectivity across individuals and species

   Luppi, Golkowski, Ranft et al. · Nature Human Behaviour · 2025

   Using fMRI under sevoflurane and propofol, the study found anaesthesia reduces the uniqueness of human brain activity patterns across individuals and moves them closer to macaque patterns.

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   1. UncheckedUnder general anaesthesia, individual human brains become less self-similar and less distinguishable from one another, as measured by functional connectivity.“Using functional connectivity, we report that under anaesthesia individual brains become less self-similar and less distinguishable from each other.”
   2. UncheckedUnder anaesthesia, the loss of individual brain distinctiveness follows the sensory–association axis and tracks markers of human–primate differences.“Loss of distinctiveness is highly organized: it co-localizes with the archetypal sensory–association axis, correlating with genetic and morphometric markers of phylogenetic differences between humans and other primates.”