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Status: Unchecked ×Keyword: coupled folding and binding ×Clear all

2 claims from 1 paper

1. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   Disobind: A sequence-based, partner-dependent contact map and interface residue predictor for intrinsically disordered regions

   Majila, Ullanat and Viswanath · Cell Systems · 2026

   The authors built Disobind, a deep-learning tool that predicts contact maps and interface residues between a disordered protein region and its partner from sequences alone, and compared it with other methods.

   Unchecked2 claims
   Show 2 claims

   1. UncheckedDisobind, a sequence-based predictor, is reported to outperform AlphaFold multimer and AlphaFold3 at multiple confidence cutoffs for disordered-region binding sites.“It also outperforms AlphaFold multimer and AlphaFold3 at multiple confidence cutoffs.”
   2. Unchecked“Combining Disobind and AlphaFold-multimer predictions further improves performance.”