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1,505 claims from 935 papers are on the record. 46 have been checked so far; the other 1,459 have no check with a result yet.

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Keyword: language models ×Clear all

3 claims from 2 papers

1. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   Language models generalize beyond natural proteins

   Verkuil, Kabeli, Du et al. · bioRxiv (Cold Spring Harbor Laboratory) · 2022

   The paper reports that language models trained only on protein sequences can design new proteins, including from a specified backbone or by unconstrained generation, many of which worked in lab tests.

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   1. UncheckedOf 228 language-model-generated proteins tested in the lab, 152 (67%) formed a soluble, single-unit (monomeric) species by size exclusion chromatography.“A total of 228 generated proteins are evaluated experimentally with high overall success rates (152/228 or 67%) in producing a soluble and monomeric species by size exclusion chromatography.”
   2. UncheckedOf 152 language-model-designed proteins that worked in experiments, 35 had no significant sequence match to any known natural protein.“Out of 152 experimentally successful designs, 35 have no significant sequence match to known natural proteins.”

2. Materials Science › Machine Learning in Materials Science

   Leveraging language representation for materials exploration and discovery

   Qu, Xie, Ciesielski, Porter, Toberer and Ertekin · npj Computational Materials · 2024

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   1. Unchecked“The contextual knowledge encoded in these language representations conveys information about material properties and structures, enabling both similarity analysis to recall relevant candidates based on a query material and multi-task learning to share inform…