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Status: Unchecked ×Keyword: latent space compression ×Clear all

2 claims from 1 paper

1. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   Tokenized and continuous embedding compressions of protein sequence and structure

   Lu, Yan, Yang et al. · Patterns · 2025

   The paper compresses the latent space of the protein folding model ESMFold into smaller continuous and tokenized embeddings, called CHEAP, that keep structure information and work on function and localization tasks.

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   1. Unchecked“In continuous compression schemes, the ESMFold latent space can be reduced by factors of 128 × along the channel and 8 × along the length while retaining structure information at <2 Å scale accuracy and performing competitively on protein function and locali…
   2. UncheckedThe authors build a discrete all-atom protein structure vocabulary that reconstructs structures accurately and can be obtained from the sequence alone.“In discrete compression schemes, we construct a tokenized all-atom structure vocabulary that retains high reconstruction accuracy, thus introducing a tokenized representation of an all-atom structure that can be obtained from the sequence alone.”