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Keyword: model quality assessment ×Clear all

2 claims from 2 papers

1. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   lDDT: a local superposition-free score for comparing protein structures and models using distance difference tests

   Mariani, Biasini, Barbato and Schwede · Bioinformatics · 2013

   The paper introduces lDDT, a score that compares protein models with reference structures using local distance differences rather than superposition, and presents it as a robust tool for automated assessment.

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   1. UncheckedThe lDDT score is reported to judge local accuracy of protein models well, even with domain movements, while still agreeing with global measures.“We demonstrate that lDDT is well suited to assess local model quality, even in the presence of domain movements, while maintaining good correlation with global measures.”

2. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   Challenges in bridging the gap between protein structure prediction and functional interpretation

   Váradi, Tsenkov and Velankar · Proteins Structure Function and Bioinformatics · 2023

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   1. Unchecked“Thus, challenges persist, particularly in capturing protein dynamics, predicting multi‐chain structures, interpreting protein function, and assessing model quality.”