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Status: Unchecked Keyword: prefrontal cortex maturation Clear all
3 claims from 1 paper
Neuroscience › Functional Brain Connectivity Studies
Functional network modules overlap and are linked to interindividual connectome differences during human brain development
Lei, Liao, Liang et al. · PLoS Biology · 2024
Using longitudinal MRI from 305 children aged 6 to 14, the study mapped overlapping functional brain modules, how they develop, and how they relate to gray and white matter features.
Unchecked3 claimsShow 3 claims
- UncheckedIn children, brain regions differ in how many functional modules they join: more in attention, somatomotor and subcortical areas, fewer in visual and default-mode areas.“We showed a regionally heterogeneous spatial topography of the overlapping extent of brain nodes in module affiliations in children, with higher entropy (i.e., more module involvement) in the ventral attention, somatomotor, and subcortical regions and lower entropy (i.e., less module involvement) i…”
- UncheckedIn children aged 6 to 14, brain regions' involvement in overlapping functional modules changed linearly with age, falling in some areas and rising in others.“The overlapping modules developed in a linear, spatially dissociable manner, with decreased entropy (i.e., decreased module involvement) in the dorsomedial prefrontal cortex, ventral prefrontal cortex, and putamen and increased entropy (i.e., increased module involvement) in the parietal lobules an…”
- UncheckedIn children aged 6 to 14, overlapping functional brain modules tracked chronological age and were predicted from combined gray and white matter features.“The overlapping modular patterns captured individual brain maturity as characterized by chronological age and were predicted by integrating gray matter morphology and white matter microstructural properties.”
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