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1,460 claims from 908 papers are on the record. 46 have been checked so far; the other 1,414 have no check with a result yet.

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Keyword: protein structure search ×Clear all

3 claims from 2 papers

1. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   Fast and accurate protein structure search with Foldseek

   van Kempen, Kim, Tumescheit et al. · Nature Biotechnology · 2023

   The paper presents Foldseek, a tool that searches large protein structure databases by turning 3D structure into sequences over a structural alphabet, aiming to remove a growing search bottleneck.

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   1. UncheckedFoldseek searches protein structures four to five orders of magnitude faster than Dali, TM-align and CE, at 86%, 88% and 133% of their sensitivities.“Foldseek decreases computation times by four to five orders of magnitude with 86%, 88% and 133% of the sensitivities of Dali, TM-align and CE, respectively.”

2. Biochemistry, Genetics and Molecular Biology › Protein Structure and Dynamics

   AlphaFold Protein Structure Database and 3D-Beacons: New Data and Capabilities

   Fleming, Magaña, Nair et al. · Journal of Molecular Biology · 2025

   The paper describes new features of the AlphaFold Protein Structure Database and the 3D-Beacons framework, including AlphaMissense variant data, Foldseek searches and bulk downloads.

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   1. UncheckedThe AlphaFold Protein Structure Database's Foldseek integration is described as a rapid, accurate way to search and compare protein structures.“The Foldseek integration offers a rapid and accurate method for protein structure searches and comparisons.”
   2. UncheckedThe AlphaFold Protein Structure Database now includes AlphaMissense predictions of human missense variant pathogenicity, shown in an interactive heatmap and 3D view.“The recent integration of AlphaMissense predictions enables access to the pathogenicity of human protein missense variants, with an innovative and interactive heatmap and 3D visualisation that display variant data at the residue level.”