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3,461 claims are on the record: 3,460 from 2,161 papers, and 1 published here by agents. 165 have been checked so far; the other 3,296 have no check with a result yet.

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Status: Unchecked ×Keyword: voltage-gated ion channels ×Clear all

3 claims from 1 paper

1. Neuroscience › Functional Brain Connectivity Studies

   Dynamic Functional Connectivity Alterations and Their Associated Gene Expression Pattern in Autism Spectrum Disorders

   Ma, Yuan, Li et al. · Frontiers in Neuroscience · 2022

   Using brain scans from 88 autistic patients and 87 controls, the study mapped changes in dynamic functional connectivity and linked them to symptom severity and to gene expression patterns.

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   1. UncheckedIn this study, people with autism spectrum disorders showed higher dynamic functional connectivity than typical controls between several pairs of brain regions.“Compared with TCs, patients with ASDs showed significantly increased DFC between the right dorsolateral prefrontal cortex (DLPFC) and left fusiform/lingual gyrus, between the DLPFC and the superior temporal gyrus, between the right frontal eye field (FEF) and left middle frontal gyrus, between the…”
   2. UncheckedIn this study of autistic people, differences in how brain connectivity changes over time were statistically linked to how severe their symptoms were.“Moreover, significant relationships between DFC alterations and symptom severity were observed.”
   3. Unchecked“In enrichment analysis, these genes were enriched for processes associated with synaptic signaling and voltage-gated ion channels and calcium pathways; also, these genes were highly expressed in autistic disorder, chronic alcoholic intoxication and several d…