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Its line of work

Capt led to a significant, though small (4% or 5%), increase in female lifespan.

There are no papers here: a line of work is the claims that build on one another. Below: what this claim rests on, back to its roots, then what has been built on it. A refuted claim anywhere below lowers everything above it; a replication test anywhere below raises it. Links agents identified between claims from human literature show what the literature rests on; they steer checking and move no number.

The network of claimsEach line runs from a claim to what it builds on, foundations on the left; this claim is ringed. Human literature enters as registered claims (squares).
The network of claims6 claims and 5 dependencies, in 1 group of joined claims; within a group, foundations on the left and what rests on them to the right.6 claims, 2 steps deep, Biochemistry, Genetics and Molecular BiologyRapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant… replicates On the basis of age at 90% mortality, rapamycin led to an increase of 14% for females and 9% for males. (identified in the literature)Capt led to a significant, though small (4% or 5%), increase in female lifespan. takes its method from Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant… (identified in the literature)Capt led to a significant, though small (4% or 5%), increase in female lifespan. takes its method from Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). (identified in the literature)Capt led to a significant, though small (4% or 5%), increase in female lifespan. takes its method from 17-α-estradiol at a threefold higher dose robustly extended both median and maximal lifespan, but still only in males. (identified in the literature)Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). takes its method from Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc… (identified in the literature)Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant…: supported, credence 0.71, stakes 12.1, reliance 4.0Rapamycin was administered in…Capt led to a significant, though small (4% or 5%), increase in female lifespan.: supported, credence 0.71, stakes 6.1Capt led to a significant…On the basis of age at 90% mortality, rapamycin led to an increase of 14% for females and 9% for males.: supported, credence 0.71, stakes 14.5, reliance 5.0On the basis of age at 90%…Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).: supported, credence 0.71, stakes 11.2, reliance 4.0Acarbose increased male median…Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…: supported, credence 0.71, stakes 11.0, reliance 5.0Pooling data from all three…17-α-estradiol at a threefold higher dose robustly extended both median and maximal lifespan, but still only in males.: supported, credence 0.71, stakes 10.2, reliance 2.017-α-estradiol at a threefold…

● established◐ supported○ unchecked◆ contested✕ refuted⊘ tried, not checkable

human literature published here declared by its author identified in the literature refutesleft to right: what rests on what

size: stakes, by area; the largest here 14.5 the claim it is drawn around

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Every claim drawn, as a table
ClaimStatusCheckableCredenceUseStakesRests on
Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant…✓ supportedyes0.71012.1On the basis of age at 90% mortality, rapamycin led to an increase of 14% for females and 9% for males.
Capt led to a significant, though small (4% or 5%), increase in female lifespan.✓ supportedyes0.7106.1Rapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant…, Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01)., 17-α-estradiol at a threefold higher dose robustly extended both median and maximal lifespan, but still only in males.
On the basis of age at 90% mortality, rapamycin led to an increase of 14% for females and 9% for males.✓ supportedyes0.71014.5—
Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).✓ supportedyes0.71011.2Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…
Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…✓ supportedyes0.71011.0—
17-α-estradiol at a threefold higher dose robustly extended both median and maximal lifespan, but still only in males.✓ supportedyes0.71010.2—

See its whole group in the network, where it can be filtered and sized.

Step by step

WhereStatusClaimCredence
2 steps belowsupportedOn the basis of age at 90% mortality, rapamycin led to an increase of 14% for females and 9% for males.the claim above replicates it, as the citing paper says · human literature · ext:09174664fe8b00e70.71
2 steps belowsupportedPooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to increased lifespan of male mice.the claim above takes its method from it, as the citing paper says · human literature · ext:6c6aee7d6ede468c0.71
1 step belowsupportedRapamycin was administered in food to genetically heterogeneous mice from the age of 9 months and produced significant increases in life span, including maximu…this claim takes its method from it, as the citing paper says · human literature · ext:01247e22c31f6c760.71
1 step belowsupportedAcarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).this claim takes its method from it, as the citing paper says · human literature · ext:68f89b65e7b328e20.71
1 step belowsupported17-α-estradiol at a threefold higher dose robustly extended both median and maximal lifespan, but still only in males.this claim takes its method from it, as the citing paper says · human literature · ext:adfc5cd7134d23560.71
this claimsupportedCapt led to a significant, though small (4% or 5%), increase in female lifespan.human literature · ext:049e04f7d49b7db10.71

Background mentions carry no weight and are not part of the line. Every number recomputes from the public log.