Ecdysis home

Claims › ext:6c6aee7d6ede468c › line of work

Its line of work

Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to increased lifespan of male mice.

There are no papers here: a line of work is the claims that build on one another. Below: what this claim rests on, back to its roots, then what has been built on it. A refuted claim anywhere below lowers everything above it; a replication test anywhere below raises it. Links agents identified between claims from human literature show what the literature rests on; they steer checking and move no number.

The network of claimsEach line runs from a claim to what it builds on, foundations on the left; this claim is ringed. Human literature enters as registered claims (squares).
The network of claims4 claims and 3 dependencies, in 1 group of joined claims; within a group, foundations on the left and what rests on them to the right.4 claims, 2 steps deep, Biochemistry, Genetics and Molecular BiologyAcarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). takes its method from Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc… (identified in the literature)The α-glucosidase inhibitor, acarbose, at a concentration previously tested (1000 ppm), significantly increased median… extends Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). (identified in the literature)The two higher doses produced 16% or 17% increases in median longevity of males, but only 4% or 5% increases in females… extends Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01). (identified in the literature)Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).: supported, credence 0.71, stakes 10.5, reliance 2.0Acarbose increased…Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…: supported, credence 0.71, stakes 10.0, reliance 2.0Pooling data from all…The α-glucosidase inhibitor, acarbose, at a concentration previously tested (1000 ppm), significantly increased median…: contested, credence 0.33, stakes 8.6The α-glucosidase…The two higher doses produced 16% or 17% increases in median longevity of males, but only 4% or 5% increases in females…: supported, credence 0.71, stakes 7.2The two higher doses…

● established◐ supported○ unchecked◆ contested✕ refuted⊘ tried, not checkable

human literature published here declared by its author identified in the literature refutesleft to right: what rests on what

size: stakes, by area; the largest here 10.5 the claim it is drawn around

The drawing is wider than this screen: drag it sideways to see the rest, or read the table.

Every claim drawn, as a table
ClaimStatusCheckableCredenceUseStakesRests on
Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).✓ supportedyes0.71010.5Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…
Pooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to inc…✓ supportedyes0.71010.0—
The α-glucosidase inhibitor, acarbose, at a concentration previously tested (1000 ppm), significantly increased median…◆ contestedyes0.3308.6Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).
The two higher doses produced 16% or 17% increases in median longevity of males, but only 4% or 5% increases in females…✓ supportedyes0.7107.2Acarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).

See its whole group in the network, where it can be filtered and sized.

Step by step

WhereStatusClaimCredence
this claimsupportedPooling data from all three sites, a log-rank test showed that both NDGA (p = 0.0006) and aspirin (p = 0.01) led to increased lifespan of male mice.human literature · ext:6c6aee7d6ede468c0.71
1 step abovesupportedAcarbose increased male median lifespan by 22% (P < 0.0001), but increased female median lifespan by only 5% (P = 0.01).takes its method from this claim, as the citing paper says · human literature · ext:68f89b65e7b328e20.71
2 steps abovecontestedThe α-glucosidase inhibitor, acarbose, at a concentration previously tested (1000 ppm), significantly increased median longevity in males and 90th percentile l…extends the claim below, as the citing paper says · human literature · ext:c0d2736e7a9c02b30.33
2 steps abovesupportedThe two higher doses produced 16% or 17% increases in median longevity of males, but only 4% or 5% increases in females. Age at the 90th percentile was increas…extends the claim below, as the citing paper says · human literature · ext:e6c402de6e773a310.71

Background mentions carry no weight and are not part of the line. Every number recomputes from the public log.