| unchecked | Semisupervised models that combine our data with the rich sequence representations from large protein language models predict orthologous ADK-sequence catalytic parameters better than existing approaches.DOI 10.1126/science.adu1058 · ext:568948cc79653c30 | 0.55 | 5.46 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | These results challenge long-standing hypotheses in enzyme adaptation, demonstrating that thermophilic enzymes are not universally slower than their mesophilic counterparts.DOI 10.1126/science.adu1058 · ext:dee3e9277da86ed7 | 0.55 | 5.46 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | In addition, we find that the use of a symmetric exponential loss reduces the smoothing of NWM forecasts with lead time.arXiv 2205.10972 · ext:c533064172090b21 | 0.55 | 5.43 | 0 | 0 | Earth and Planetary Sciences | 11 Oct 2026 |
| unchecked | We find that training models to minimize custom losses tailored to emphasize extremes leads to significant skill improvements in the heat wave prediction task, compared to NWMs trained on the mean squared error loss.arXiv 2205.10972 · ext:2a3b700e6ce302dc | 0.55 | 5.43 | 0 | 0 | Earth and Planetary Sciences | 11 Oct 2026 |
| unchecked | Questions of debt sustainability and default will remain acute in both developing and advanced economies.DOI 10.1257/jel.20211362 · conceptual · ext:3cc4d6ea6454b5e8 | 0.55 | 5.43 | 0 | 0 | Economics, Econometrics and Finance | 9 Oct 2026 |
| unchecked | Many of these characteristics were already present in historical debt crises and are likely to remain relevant in the future.DOI 10.1257/jel.20211362 · conceptual · ext:c7dceae889c97e59 | 0.55 | 5.43 | 0 | 0 | Economics, Econometrics and Finance | 9 Oct 2026 |
| unchecked | To demonstrate the effectiveness of OTO, we train and compress full models simultaneously from scratch without fine-tuning for inference speedup and parameter reduction, and achieve state-of-the-art results on VGG16 for CIFAR10, ResNet50 f…arXiv 2107.07467 · ext:014f2715260b6de0 | 0.55 | 5.43 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | OTO contains two keys: (i) we partition the parameters of DNNs into zero-invariant groups, enabling us to prune zero groups without affecting the output; and (ii) to promote zero groups, we then formulate a structured-sparsity optimization…arXiv 2107.07467 · ext:64766086f7bad77f | 0.55 | 5.43 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | Our taxonomy is based on an extensive literature review of generalisation research, and contains five axes along which studies can differ: their main motivation, the type of generalisation they investigate, the type of data shift they cons…arXiv 2210.03050 · conceptual · ext:f0ea978c8bc81db1 | 0.55 | 5.39 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | However, we did not find evidence of generalist clinical LLMs successfully applicable to a wide range of clinical tasks.DOI 10.2196/71916 · ext:477dceb578e1f7a4 | 0.55 | 5.36 | 0 | 0 | Medicine | 9 Oct 2026 |
| unchecked | GPT-3.5 and GPT-4 were the most versatile models in the 5-stage clinical workflow, applied to 52% (29/56) and 71% (40/56) of the clinical subtasks, respectively, and they performed best in 29% (16/56) and 54% (30/56) of the clinical subtas…DOI 10.2196/71916 · ext:fe8a52e182abed59 | 0.55 | 5.36 | 0 | 0 | Medicine | 9 Oct 2026 |
| unchecked | A fly-by also naturally explains the puzzling fact that Neptune has a higher mass than Uranus.arXiv 1807.02960 · conceptual · ext:44539a81cd8575b1 | 0.55 | 5.36 | 0 | 0 | Physics and Astronomy | 7 Oct 2026 |
| unchecked | After multiple rounds of high-throughput experiments, TeleProt found a significantly better top-performing enzyme than directed evolution (DE), had a better hit rate at finding diverse, high-activity variants, and was even able to design a…DOI 10.1016/j.cels.2025.101236 · ext:8525876ecd4ed8fc | 0.55 | 5.32 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 9 Oct 2026 |
| unchecked | Most speed cells located in entorhinal cortex layer 2 represented speed prospectively, whereas those in the CA1 and entorhinal cortex layers 3 and 5 represented speed retrospectively.DOI 10.1038/s41598-020-58194-1 · ext:0bc8727f8af890be | 0.55 | 5.32 | 0 | 0 | Neuroscience | 9 Oct 2026 |
| unchecked | The performance evaluation, based on latitude-weighted root mean square error (RMSE) and anomaly correlation coefficient (ACC), demonstrates that FuXi has comparable forecast performance to ECMWF EM in 15-day forecasts, making FuXi the fir…arXiv 2306.12873 · ext:6f3b729e223d0878 | 0.55 | 5.32 | 0 | 1 | Earth and Planetary Sciences | 7 Oct 2026 |
| unchecked | For the 11 typhoons in 2023, FengWu demonstrates the most accurate track prediction; however, it also has the largest intensity errors.DOI 10.1038/s41612-024-00769-0 · ext:58f34773b53063b8 | 0.55 | 5.32 | 0 | 0 | Earth and Planetary Sciences | 7 Oct 2026 |
| unchecked | A multi-model ensemble, constructed by averaging predictions from the five models, demonstrates superior performance, rivaling that of FengWu.DOI 10.1038/s41612-024-00769-0 · ext:fd50eaf4c5b6a935 | 0.55 | 5.32 | 0 | 0 | Earth and Planetary Sciences | 7 Oct 2026 |
| unchecked | We prove that the SAT-UNSAT phase transition threshold of an infinite chain is identical to the one of the individual standard model, and is therefore not affected by spatial coupling.arXiv 1112.6320 · ext:2c4e37a8a2435566 | 0.55 | 5.32 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | Although positively selected residues are distributed across various structural elements, enzyme evolution is constrained by reaction mechanisms, interactions with metal ions and inhibitors, metabolic flux variability and biosynthetic cost.DOI 10.1038/s41586-025-09205-6 · conceptual · ext:10be07b79697e833 | 0.55 | 5.31 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | By linking sequence divergence in structurally conserved regions to a variety of metabolic properties of the enzymes, we reveal that metabolism shapes structural evolution across multiple scales, from species-wide metabolic specialization…DOI 10.1038/s41586-025-09205-6 · ext:a14cdba7dbe2d206 | 0.55 | 5.31 | 2 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | We show that this bound is tight up to an absolute constant factor in the exponent.arXiv 1710.03745 · conceptual · ext:52a341720d4a6b35 | 0.55 | 5.25 | 0 | 0 | Mathematics | 10 Oct 2026 |
| unchecked | We show that every $n$-vertex graph with bounded VC-dimension contains a clique or an independent set of size at least $e^{(\log n)^{1 - o(1)}}$.arXiv 1710.03745 · ext:b67baf930dda4110 | 0.55 | 5.25 | 0 | 0 | Mathematics | 10 Oct 2026 |
| unchecked | Simulations show that the model can learn hundreds of objects even when object features alone are insufficient for disambiguation.DOI 10.3389/fncir.2019.00022 · ext:e91498b4a99fb13e | 0.55 | 5.25 | 0 | 0 | Neuroscience | 9 Oct 2026 |
| unchecked | Our findings indicate that in these parameterizations, the deviation from ($w_0$,$w_{1}$)=(-1,0) becomes more pronounced when using the combined data from DESI BAO, SNe Ia, and QSO compilations.arXiv 2412.04830 · ext:cea5bdccb4c467cd | 0.55 | 5.25 | 1 | 0 | Physics and Astronomy | 8 Oct 2026 |
| unchecked | Despite its promise, the development of EmAI for healthcare is hindered by critical challenges such as safety concerns, gaps between simulation platforms and real-world applications, the absence of standardized benchmarks, and uneven progr…arXiv 2501.07468 · conceptual · ext:901d39e60f25f427 | 0.55 | 5.25 | 0 | 0 | Medicine | 7 Oct 2026 |
| unchecked | Further extensive experiments with popular CNNs on CIFAR-10 and ImageNet datasets show that IncReg achieves comparable to even better results compared with state-of-the-arts.DOI 10.1109/jstsp.2019.2961233 · ext:6a3d0d5a1dee58a2 | 0.55 | 5.25 | 0 | 0 | Computer Science | 6 Oct 2026 |
| unchecked | In these same mice, we identified 458 genes differentially expressed with age in MEC, 61 of which had expression correlated with spatial coding quality.DOI 10.1038/s41467-025-63229-0 · ext:e936fd030a4eca7b | 0.55 | 5.23 | 0 | 0 | Neuroscience | 9 Oct 2026 |
| unchecked | Additionally, aged grid networks shifted firing patterns often, but with poor alignment to context changes.DOI 10.1038/s41467-025-63229-0 · ext:d2c242653616c579 | 0.55 | 5.23 | 0 | 0 | Neuroscience | 9 Oct 2026 |
| unchecked | In aged grid cells, we observed impaired stabilization of context-specific spatial firing, correlated with spatial memory deficits.DOI 10.1038/s41467-025-63229-0 · ext:ce669ee3d1e4574a | 0.55 | 5.23 | 1 | 0 | Neuroscience | 9 Oct 2026 |
| unchecked | FuXi Weather outperforms the European Centre for Medium-Range Weather Forecasts high-resolution forecasts beyond day one in observation-sparse regions such as central Africa, highlighting its potential to improve forecasts where observatio…DOI 10.1038/s41467-025-62024-1 · ext:ef45586127a28a0e | 0.55 | 5.23 | 0 | 0 | Earth and Planetary Sciences | 9 Oct 2026 |
| unchecked | FuXi Weather generates reliable 10-day forecasts at 0.25° resolution using fewer observations than conventional NWP systems.DOI 10.1038/s41467-025-62024-1 · ext:c55e22589de1c6c0 | 0.55 | 5.23 | 0 | 0 | Earth and Planetary Sciences | 9 Oct 2026 |
| unchecked | Including Planck CMB data, SDSS BAO data, and DES $3\times2$-point data gives $(Ω_{\rm M},w)=(0.321\pm0.007,-0.941\pm0.026)$.arXiv 2401.02929 · ext:ab71233fdee65185 | 0.55 | 5.21 | 0 | 0 | Physics and Astronomy | 7 Oct 2026 |
| unchecked | Supernova data alone now require acceleration ($q_0<0$ in $Λ$CDM) with over $5σ$ confidence.arXiv 2401.02929 · ext:25dae19a11cd76e8 | 0.55 | 5.21 | 0 | 0 | Physics and Astronomy | 7 Oct 2026 |
| unchecked | However, the interpretation of exoplanet data requires the development and validation of exoplanet models that depend on in-situ data that, in the foreseeable future, are only obtainable from our Solar System.arXiv 2012.11628 · conceptual · ext:0305d631806e9fde | 0.55 | 5.17 | 0 | 0 | Physics and Astronomy | 11 Oct 2026 |
| unchecked | We prove that there exists a constant $c$ such that for all natural numbers $d$ and $r$, every $d$-degenerate graph $H$ of chromatic number $r$ with $|V(H)| \ge 2^{d^22^{cr}}$ has Ramsey number at most $2^{d2^{cr}} |V(H)|$.arXiv 1505.04773 · conceptual · ext:8749d2d40f49ce9c | 0.55 | 5.17 | 0 | 0 | Mathematics | 10 Oct 2026 |
| unchecked | This has led the latter to under-appreciate the relevance and complexity of spatial behavior, and to focus too narrowly on characterizing neural representations of space-disconnected from the computations these representations are meant to…DOI 10.1016/j.neubiorev.2023.105200 · conceptual · ext:0243adbc6b72442f | 0.55 | 5.17 | 0 | 0 | Neuroscience | 8 Oct 2026 |
| unchecked | We show that the threshold $\alpha_{\rm sat}(k)$ is given explicitly by the one-step replica symmetry breaking prediction from statistical physics.DOI 10.4007/annals.2022.196.1.1 · ext:e70d9e1009d1fa0b | 0.55 | 5.13 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | We establish the satisfiability threshold for random $k$-SAT for all $k\ge k_0$, with $k_0$ an absolute constant.DOI 10.4007/annals.2022.196.1.1 · conceptual · ext:661f77ba97654e16 | 0.55 | 5.13 | 0 | 0 | Computer Science | 7 Oct 2026 |
| unchecked | We show that SWD compares favorably to state-of-the-art approaches, in terms of performance-to-parameters ratio, on the CIFAR-10, Cora, and ImageNet ILSVRC2012 datasets.arXiv 2011.10520 · ext:ad7d5b1a84275cbb | 0.55 | 5.13 | 0 | 0 | Medicine | 6 Oct 2026 |
| unchecked | Thus, challenges persist, particularly in capturing protein dynamics, predicting multi‐chain structures, interpreting protein function, and assessing model quality.DOI 10.1002/prot.26614 · conceptual · ext:e9d30f0882a66c8c | 0.55 | 5.09 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | We find that ML weather prediction models locally achieve similar accuracy to HRES on the record-shattering Pacific Northwest heatwave but underperform when aggregated over space and time.arXiv 2404.17652 · ext:9195793000ae2f5e | 0.55 | 5.09 | 0 | 0 | Earth and Planetary Sciences | 9 Oct 2026 |
| unchecked | Notably, data-driven models appear to perform best for temperature extremes in regions closer to the tropics and at shorter lead times.DOI 10.5194/gmd-17-7915-2024 · ext:eaba3b577b04f303 | 0.55 | 5.09 | 0 | 0 | Earth and Planetary Sciences | 7 Oct 2026 |
| unchecked | However, the performance of data-driven models varies by region, type of extreme event, and forecast lead time.DOI 10.5194/gmd-17-7915-2024 · conceptual · ext:f87f63ce04ac8a90 | 0.55 | 5.09 | 0 | 0 | Earth and Planetary Sciences | 7 Oct 2026 |
| unchecked | ACE2 generates emergent phenomena such as tropical cyclones, the Madden Julian Oscillation, and sudden stratospheric warmings.DOI 10.1038/s41612-025-01090-0 · ext:5e8859861dbf34e1 | 0.55 | 5.04 | 0 | 0 | Environmental Science | 9 Oct 2026 |
| unchecked | It exactly conserves global dry air mass and moisture and can be stepped forward stably for arbitrarily many steps with a throughput of about 1500 simulated years per wall clock day.DOI 10.1038/s41612-025-01090-0 · ext:b6cf636efc865b43 | 0.55 | 5.04 | 0 | 0 | Environmental Science | 9 Oct 2026 |
| unchecked | Evolutionary analysis suggests that most clusters are ancient in origin but 4% seem species specific, representing lower quality predictions or examples of de-novo gene birth.DOI 10.1101/2023.03.09.531927 · ext:d72297f613f141bf | 0.55 | 5.00 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | Clusters without annotation tend to have few representatives covering only 4% of all proteins in the AFDB.DOI 10.1101/2023.03.09.531927 · ext:5d744bb0bcc67fb1 | 0.55 | 5.00 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | Using this method we have clustered all structures in AFDB, identifying 2.27M non-singleton structural clusters, of which 31% lack annotations representing likely novel structures.DOI 10.1101/2023.03.09.531927 · ext:23a0f65d627bc2ab | 0.55 | 5.00 | 0 | 0 | Biochemistry, Genetics and Molecular Biology | 10 Oct 2026 |
| unchecked | In addition, our ELC improves the inference speed by 2× on Jetson AGX Xavier edge device.DOI 10.1109/tip.2023.3302519 · ext:b26c6d5653370778 | 0.55 | 5.00 | 0 | 0 | Computer Science | 9 Oct 2026 |
| unchecked | Experimental results conducted on two datasets demonstrate that our method retains superior performance with a FLOPs reduction of 74.1% for VGG-16 and 54.6% for ResNet-56, respectively.DOI 10.1109/tip.2023.3302519 · ext:178ee1433375fc9c | 0.55 | 5.00 | 0 | 0 | Computer Science | 9 Oct 2026 |